Travoprost

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Travoprost
Travoprost structure.svg
Systematic (IUPAC) name
propan-2-yl 7-[3,5-dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)
phenoxy]-but-1-enyl]-cyclopentyl]hept-5-enoate
Clinical data
Trade names Travatan
AHFS/Drugs.com monograph
MedlinePlus a602027
Pregnancy cat. C US
Legal status Rx only (US)
Routes Topical (eye drops)
Identifiers
CAS number 157283-68-6 YesY
ATC code S01EE04
PubChem CID 5282226
DrugBank DB00287
ChemSpider 4445407 YesY
UNII WJ68R08KX9 YesY
KEGG D01964 YesY
ChEBI CHEBI:746859 YesY
ChEMBL CHEMBL1200799 N
Chemical data
Formula C26H35F3O6 
Mol. mass 500.548 g/mol
 N (what is this?)  (verify)
One 2.5 ml dropperette of Alcon Travatan

Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a synthetic prostaglandin analog (or more specifically, an analog of prostaglandin F)[1][2] that works by increasing the outflow of aqueous fluid from the eyes.[3] It is also known by the brand names of Travatan and Travatan Z, manufactured by Alcon, and Travo-Z, manufactured by Micro Labs.

Side effects[edit]

Possible side effects of this medication are:

  • May cause blurred vision
  • May cause eyelid redness
  • May permanently darken eyelashes
  • May cause eye discomfort
  • May eventually cause permanent darkening of the iris to brown (heterochromia)
  • May cause a temporary burning sensation during use
  • May cause thickening of the eyelashes
  • May cause inflammation of the prostate gland, restricting urine flow (BPH)

References[edit]

  1. ^ Alcon Laboratories, Inc. (September 2011). "TRAVATAN - travoprost solution". DailyMed. Bethesda, MD: U.S. National Library of Medicine. Retrieved 2011-09-30. 
  2. ^ Alcon Laboratories, Inc. (September 2011). "TRAVATAN Z (travoprost) solution". DailyMed. Bethesda, MD: U.S. National Library of Medicine. Retrieved 2011-09-30. 
  3. ^ AHFS Consumer Medication Information (2011-01-01). "Travoprost Ophthalmic". MedlinePlus. Bethesda, MD: U.S. National Library of Medicine. Retrieved 2011-09-30.