Travoprost
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| Systematic (IUPAC) name | |
| propan-2-yl 7-[3,5-dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl) phenoxy]-but-1-enyl]-cyclopentyl]hept-5-enoate |
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| Clinical data | |
| Trade names | Travatan |
| AHFS/Drugs.com | monograph |
| MedlinePlus | a602027 |
| Pregnancy cat. | C US |
| Legal status | Rx only (US) |
| Routes | Topical (eye drops) |
| Identifiers | |
| CAS number | 157283-68-6  |
| ATC code | S01EE04 |
| PubChem | CID 5282226 |
| DrugBank | APRD01271 |
| ChemSpider | 4445407 |
| UNII | WJ68R08KX9 |
| KEGG | D01964 |
| ChEBI | CHEBI:746859 |
| ChEMBL | CHEMBL1200799  |
| Chemical data | |
| Formula | C26H35F3O6 |
| Mol. mass | 500.548 g/mol |
| SMILES | eMolecules & PubChem |
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Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a synthetic prostaglandin analog (or more specifically, an analog of prostaglandin F2α)[1][2] that works by increasing the outflow of aqueous fluid from the eyes.[3] It is also known by the brand names of Travatan and Travatan Z, manufactured by Alcon, and Travo-Z, manufactured by Micro Labs.
[edit] Side effects
Possible side effects of this medication are:
- May cause blurred vision
- May cause eyelid redness
- May permanently darken eyelashes
- May cause eye discomfort
- May eventually cause permanent darkening of the iris to brown (heterochromia)
- May cause a temporary burning sensation during use
- May cause thickening of the eyelashes
- May cause inflammation of the prostate gland, restricting urine flow (BPH)
[edit] References
- ^ Alcon Laboratories, Inc. (September 2011). "TRAVATAN - travoprost solution". DailyMed. Bethesda, MD: U.S. National Library of Medicine. http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=338e7ff4-0d91-4208-a45d-bfa2be52334d. Retrieved 2011-09-30.
- ^ Alcon Laboratories, Inc. (September 2011). "TRAVATAN Z (travoprost) solution". DailyMed. Bethesda, MD: U.S. National Library of Medicine. http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=5549684b-1724-45ca-b67b-590c62b7c149. Retrieved 2011-09-30.
- ^ AHFS Consumer Medication Information (2011-01-01). "Travoprost Ophthalmic". MedlinePlus. Bethesda, MD: U.S. National Library of Medicine. http://www.nlm.nih.gov/medlineplus/druginfo/meds/a602027.html. Retrieved 2011-09-30.
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