Tafluprost

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Tafluprost
Tafluprost structure.svg
Systematic (IUPAC) name
isopropyl (5Z)-7-{(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl}hept-5-enoate
Clinical data
Trade names Saflutan, Taflotan, Tapros, Zioptan
AHFS/Drugs.com International Drug Names
  • US: C (Risk not ruled out)
Topical (eye drops)
Identifiers
209860-87-7
S01EE05
PubChem CID 6433101
ChemSpider 8044182
UNII 1O6WQ6T7G3 YesY
ChEBI CHEBI:66899 YesY
ChEMBL CHEMBL1963683
Chemical data
Formula C25H34F2O5
452.531266 g/mol

Tafluprost (trade names Taflotan, marketed by Santen Pharmaceutical and Zioptan, by Merck (U.S.)) is a prostaglandin analogue used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure by increasing the outflow of aqueous fluid from the eyes.[1][2]

Taflotan contains 15 µg/ml Tafluprost. Taflotan sine is a preservative-free, single-dose formulation containing 0.3 ml per dose.[3]

References[edit]

  1. ^ Schubert-Zsilavecz, M, Wurglics, M, Neue Arzneimittel 2008/2009
  2. ^ Santen Home Page
  3. ^ Gelbe Liste (in German)