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Tritoqualine

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Tritoqualine
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • 7-amino-4,5,6-triethoxy-3-(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-3H-isobenzofuran-1-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC26H32N2O8
Molar mass500.548 g·mol−1
3D model (JSmol)
  • CCOC1=C(C(=C(C2=C1C(OC2=O)C3C4=C(C5=C(C=C4CCN3C)OCO5)OC)N)OCC)OCC

Tritoqualine, also known as hypostamine, is an inhibitor of the enzyme histidine decarboxylase and therefore an atypical antihistamine, used for the treatment of urticaria and allergic rhinitis[1] with no known adverse effects.[citation needed]

References

  1. ^ Pradalier A, Hentschel V, Prouzeau S, Legallais D, Lefrancois G (April 2003). "Randomized, placebo controlled study of tritoqualine (hypostamine*) in the treatment of perennial allergic rhinitis". Revue Française d'Allergologie et d'Immunologie Clinique. 43 (3): 175–9. doi:10.1016/S0335-7457(03)00047-9.
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