Metipranolol

Metipranolol
Clinical data
Trade names	Optipranolol
AHFS/Drugs.com	Micromedex Detailed Consumer Information
MedlinePlus	a601078
ATC code	S01ED04 (WHO) C07BA68 (WHO);
Identifiers
	IUPAC name (RS)-4-{[-2-hydroxy-3-(isopropylamino)propyl]oxy}-2,3,6-trimethylphenyl acetate;
CAS Number	22664-55-7;
PubChem CID	31477;
IUPHAR/BPS	7239;
DrugBank	DB01214 ;
ChemSpider	29193 ;
UNII	X39AL81KEB;
KEGG	D02374 ;
ChEMBL	ChEMBL1291 ;
CompTox Dashboard (EPA)	DTXSID4046078 ;
ECHA InfoCard	100.041.031
Chemical and physical data
Formula	C17H27NO4
Molar mass	309.401 g/mol g·mol−1
3D model (JSmol)	Interactive image;
Chirality	Racemic mixture
	SMILES O=C(Oc1c(c(c(OCC(O)CNC(C)C)cc1C)C)C)C;
	InChI InChI=1S/C17H27NO4/c1-10(2)18-8-15(20)9-21-16-7-11(3)17(22-14(6)19)13(5)12(16)4/h7,10,15,18,20H,8-9H2,1-6H3 ; Key:BQIPXWYNLPYNHW-UHFFFAOYSA-N ;
	(verify)

Metipranolol (OptiPranolol, Betanol, Disorat, Trimepranol) is a non-selective beta blocker used in eye drops to treat glaucoma. It is rapidly metabolized into desacetylmetipranolol.^[1]

References

^ Maffei Facino, R.; Bertuletti, R.; Carini, M.; Tofanetti, O. (1980). "In vitro metabolism of methypranolol by rat liver". Analytical Chemistry Symposia Series. 4 (6): 217–223.{{cite journal}}: CS1 maint: multiple names: authors list (link)

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