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Monoclonal antibody
Type Whole antibody
Source Humanized (from rat)
Target CD2
Clinical data
ATC code none
CAS Number 288392-69-8 N
ChemSpider none
KEGG D05847 YesY
 NYesY (what is this?)  (verify)

Siplizumab (MEDI-507) is a novel monoclonal antibody with a human IgG1, kappa directed to CD2. The agent has shown potent immunomodulatory effects, selectively suppressing the function of T and NK cells, and is currently being tested as a possible treatment for psoriasis and in the prevention of graft-versus-host disease.[1]


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