BMY-14802: Difference between revisions

BMY-14802
Clinical data
ATC code	none;
Identifiers
CAS Number	105565-55-7;
CompTox Dashboard (EPA)	DTXSID70909596 ;
Chemical and physical data
Formula	C18H22F2N4O
Molar mass	348.389 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES c1cc(F)ccc1C(O)CCCN2CCN(CC2)c3ncc(F)cn3;

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Inline

Revision as of 12:24, 9 July 2010

BMY-14802 is a drug with antipsychotic effects, which acts as both a sigma receptor antagonist, and a 5-HT_1A agonist.^[1]^[2]^[3]^[4]

^ Taylor DP, Eison MS, Moon SL, Schlemmer RF, Shukla UA, VanderMaelen CP, Yocca FD, Gallant DJ, Behling SH, Boissard CG (1993). "A role for sigma binding in the antipsychotic profile of BMY 14802?". NIDA Research Monograph. 133: 125–57. PMID 8232511.{{cite journal}}: CS1 maint: multiple names: authors list (link)
^ Vanecek SA, Essman WD, Taylor DP, Woods JH (1998). "Discriminative stimulus characteristics of BMY 14802 in the pigeon". The Journal of Pharmacology and Experimental Therapeutics. 284 (1): 1–9. PMID 9435153. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
^ Kitanaka J, Kitanaka N, Tatsuta T, Hall FS, Uhl GR, Tanaka K, Nishiyama N, Morita Y, Takemura M (2009). "Sigma1 receptor antagonists determine the behavioral pattern of the methamphetamine-induced stereotypy in mice". Psychopharmacology. 203 (4): 781–92. doi:10.1007/s00213-008-1425-z. PMID 19052726. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
^ Paquette MA, Foley K, Brudney EG, Meshul CK, Johnson SW, Berger SP (2009). "The sigma-1 antagonist BMY-14802 inhibits L-DOPA-induced abnormal involuntary movements by a WAY-100635-sensitive mechanism". Psychopharmacology. 204 (4): 743–54. doi:10.1007/s00213-009-1505-8. PMC 2845289. PMID 19283364. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)

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