5-Benzyloxytryptamine

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5-Benzyloxytryptamine
5-benzyloxytryptamine.png
Systematic (IUPAC) name
2-(5-phenylmethoxy-1H-indol-3-yl)ethanamine
Clinical data
Legal status ?
Identifiers
CAS number 20776-45-8 N
ATC code ?
PubChem CID 89576
ChemSpider 80845 YesY
Chemical data
Formula C17H18N2O 
Mol. mass 266.34 g/mol
 N (what is this?)  (verify)

5-Benzyloxytryptamine (5-BT), is a tryptamine derivative which acts as an agonist at the 5-HT1D, 5-HT2 and 5-HT6 serotonin receptors.[1][2][3][4]

See also[edit]

References[edit]

  1. ^ Lyon RA, Titeler M, Seggel MR, Glennon RA (January 1988). "Indolealkylamine analogs share 5-HT2 binding characteristics with phenylalkylamine hallucinogens". European Journal of Pharmacology 145 (3): 291–7. doi:10.1016/0014-2999(88)90432-3. PMID 3350047. 
  2. ^ Peroutka SJ, McCarthy BG, Guan XM (1991). "5-benzyloxytryptamine: a relatively selective 5-hydroxytryptamine 1D/1B agent". Life Sciences 49 (6): 409–18. doi:10.1016/0024-3205(91)90582-V. PMID 1650872. 
  3. ^ Cohen ML, Schenck K, Nelson D, Robertson DW (January 1992). "Sumatriptan and 5-benzyloxytryptamine: contractility of two 5-HT1D receptor ligands in canine saphenous veins". European Journal of Pharmacology 211 (1): 43–6. doi:10.1016/0014-2999(92)90260-B. PMID 1319907. 
  4. ^ Boess FG, Monsma FJ, Carolo C, Meyer V, Rudler A, Zwingelstein C, Sleight AJ (1997). "Functional and radioligand binding characterization of rat 5-HT6 receptors stably expressed in HEK293 cells". Neuropharmacology 36 (4–5): 713–20. doi:10.1016/S0028-3908(97)00019-1. PMID 9225298.