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| birth_date = {{birth date|1913|7|24|mf=y}}
| birth_date = {{birth date|1913|7|24|mf=y}}
| birth_place = Wilkes-Barre, Pennsylvania
| birth_place = Wilkes-Barre, Pennsylvania
| death_date = {{death date and age|2010|11|16|1913|7|24|mf=y}}
| death_place = Philadelphia, Pennsylvania
| nationality = United States
| nationality = United States
| field = [[Biophysics]]<br>[[Biochemistry]]
| field = [[Biophysics]]<br>[[Biochemistry]]
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{{MedalBottom}}
{{MedalBottom}}


'''Britton Chance''' (born July 24, 1913) is the Eldridge Reeves Johnson [[Professor Emeritus]] of [[Biochemistry]] and [[Biophysics]], as well as [[Professor Emeritus]] of Physical Chemistry and Radiological Physics at the [[School of Medicine]] of the [[University of Pennsylvania]]. He was born in [[Wilkes-Barre, Pennsylvania]]. He received a [[Bachelor of Arts|B.A.]] (1935), [[Master of Arts (postgraduate)|M.A.]] (1936) and [[Doctor of Philosophy|Ph.D.]] degree in [[Physical Chemistry]] 1940 at the [[University of Pennsylvania]], where he was a member of [[St. Anthony Hall]]. He earned a second Ph.D. at [[Cambridge University]] in 1942 in Biology/[[Physiology]]. In 1952 he received his [[D.Sc.]] from Cambridge. His research interests focused on the use of [[infrared]] light to characterize the properties of various [[biological tissue|tissues]] and breast [[tumor]]s. He joined the [[United States National Academy of Sciences]] in 1952. Chance received the [[National Medal of Science]] in 1974<ref>[http://www.nsf.gov/od/nms/recip_details.cfm?recip_id=72 National Science Foundation - The President's National Medal of Science]</ref>. He was also previously elected a Foreign Member of the Royal Swedish Academy of Sciences, Medical Sciences, in 1968, as well as a Foreign Member of the Royal Society (London) in 1981.
'''Britton Chance''' (July 24, 1913 &ndash; November 16, 2010) was the Eldridge Reeves Johnson University Professor Emeritus of [[Biochemistry]] and [[Biophysics]], as well as [[Professor Emeritus]] of Physical Chemistry and Radiological Physics at the [[University of Pennsylvania School of Medicine]].


==Biography==
===Overview===
Chance was born in [[Wilkes-Barre, Pennsylvania]]. He received a [[Bachelor of Arts|B.A.]] (1935), [[Master of Arts (postgraduate)|M.A.]] (1936) and [[Doctor of Philosophy|Ph.D.]] degree in [[Physical Chemistry]] 1940 at the [[University of Pennsylvania]], where he was a member of [[St. Anthony Hall]]. He earned a second Ph.D. at [[Cambridge University]] in 1942 in Biology/[[Physiology]]. In 1952 he received his [[D.Sc.]] from Cambridge. His research interests were diverse. He was promoted as the Professor of Biophysics at [[University of Pennsylvania School of Medicine]] and appointed the second director of the Johnson Foundation, a position he held until 1983. He was then appointed E. R. Johnson Professor of Biophysics and Physical Biochemistry (later renamed as Biochemistry and Biophysics) in 1964 and University Professor in 1977.

In his early career, he was mainly working on enzyme structure and function. He had invented the now standard stopped flow device to measure the existence of the enzyme-substrate complex in enzyme reaction.<ref>[http://www.jbc.org/cgi/content/full/279/50/e10 Kresge N, Simoni RD, Hill RL. Britton Chance: Olympian and Developer of Stop-Flow Methods. J. Biol. Chem., Vol. 279, Issue 50, 10, December 10, 2004.]</ref> In later years, while retaining his interest in those fields, he also focused on metabolic control phenomena in living tissues as studied by noninvasive technique such as phosphorous NMR and optical spectroscopy and fluorometry, including the use of [[infrared]] light to characterize the properties of various [[biological tissue|tissues]] and breast [[tumor]]s.<ref>[http://www.archives.upenn.edu/faids/upt/upt50/chance_britton.html University of Pennsylvania Archival Collection]</ref>
He joined the [[United States National Academy of Sciences]] in 1952. Chance received the [[National Medal of Science]] in 1974<ref>[http://www.nsf.gov/od/nms/recip_details.cfm?recip_id=72 National Science Foundation - The President's National Medal of Science]</ref>. He was also previously elected a Foreign Member of the Royal Swedish Academy of Sciences, Medical Sciences, in 1968, as well as a Foreign Member of the Royal Society (London) in 1981.

===World War II===
During World War II, Chance worked for the [[Radiation Laboratory]] at the [[Massachusetts Institute of Technology]] which was working on the development of radar.
During World War II, Chance worked for the [[Radiation Laboratory]] at the [[Massachusetts Institute of Technology]] which was working on the development of radar.


⚫
He won a gold medal for the United States at the [[Sailing at the 1952 Summer Olympics|1952 Summer Olympics]] in the 5½ Meter Class, alongside [[Edgar White]] and [[Sumner White]]<ref>http://www.ussailing.org/Olympics/usmedals.htm</ref>.
===Olymipic===
⚫
He won a gold medal for the United States at the [[Sailing at the 1952 Summer Olympics|1952 Summer Olympics]] in the 5½ Meter Class, alongside [[Edgar White]] and [[Sumner White]]<ref>[http://www.ussailing.org/Olympics/usmedals.htm US Sailing Medalists]</ref>.


From 1995 he had been the President of the Medical Diagnostic Research Foundation (MDRF) in Philadelphia.<ref>http://www.archives.upenn.edu/people/1900s/chance_britton.html</ref>
===Death===
He died in the [[Hospital of the University of Pennsylvania]], Philadelphia in November 2010. <ref>[http://biophotonicsworld.blogspot.com/2010/11/britton-chance-1913-2010.html Britton Chance: 1913 – 2010] BioPhotonics World 2010-11-17</ref>


⚫
[[ISOTT]] established The Britton Chance Award in honor of Professor Chance's long-standing commitment, interest and contributions to the science and engineering aspects of oxygen transport to tissue and to the society. This award was first presented in 2004 during the annual conference of ISOTT in Bari, Italy.<ref>http://www.isott.info/index.php?option=com_content&task=view&id=24&Itemid=67</ref>
==Honorary degrees==
==Honorary degrees==
* MDs from: [[Karolinska Institute]] (in 1962), [[University of Düsseldorf]] (1991),[[University of Buenos Aires]] (1993), [[University of Copenhagen]] (1995), Universita Degli Studi Di Roma "Tor Vergata" (1997).
* MDs from: [[Karolinska Institute]] (in 1962), [[University of Düsseldorf]] (1991),University of Buenos Aires (1993), [[University of Copenhagen]] (1995), Universita Degli Studi Di Roma "Tor Vergata" (1997).
*D.Sc. degrees from: Medical College of Ohio at Toledo in 1974, Semmelweis University in 1976, Hahnemann Medical College in 1977, University of Pennsylvania in 1985, University of Helsinki in 1990.
*D.Sc. degrees from: Medical College of Ohio at Toledo in 1974, Semmelweis University in 1976, Hahnemann Medical College in 1977, University of Pennsylvania in 1985, University of Helsinki in 1990.


==Awards==
==Awards==
===Academic awards===
*Paul Lewis Award in Enzyme Chemistry, in 1950
* [[The Franklin Institute Awards|John Price Wetherill Medal]], in 1966
* [[The Franklin Institute Awards|John Price Wetherill Medal]], in 1966
* Gold Medal for Distinguished Service to Medicine, [[College of Physcians]], USA, in 1987.
* Gold Medal for Distinguished Service to Medicine, [[College of Physcians]], USA, in 1987.
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* ICAS Liberty Award Recipient
* ICAS Liberty Award Recipient
* Molecular Imaging Achievement Award from the [[Society for Molecular Imaging]], USA, in 2008
* Molecular Imaging Achievement Award from the [[Society for Molecular Imaging]], USA, in 2008
* Gold Medal, 1952 Summer Olympics, Sailing 5.5 Meter Class.

===Awards named after Britton Chance===
⚫
The International Society on Oxygen Transport to Tissue ([[ISOTT]]) established The Britton Chance Award in honor of Professor Chance's long-standing commitment, interest and contributions to the science and engineering aspects of oxygen transport to tissue and to the society. This award was first presented in 2004 during the annual conference of ISOTT in Bari, Italy.<ref>[http://www.isott.info/index.php?option=com_content&task=view&id=24&Itemid=67 ISOT Awards]</ref>


==References==
==References==
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==External links==
==External links==
* http://www.etaiwannews.com/etn/news_content.php?id=1174734&lang=eng_news - Feb 6, 2010 Taiwan News
⚫
* [http://www.uphs.upenn.edu/biocbiop/faculty/pages/chance.html Faculty Home Page by the Department of Biochemistry and Biophysics of Penn Medd]
* http://zippy1300.blogspot.com/2010/02/i-see-by-snailpapers-that-britton.html - Feb. 12, 2010, Taiwan Blogger
* [http://www.archives.upenn.edu/faids/upt/upt50/chance_britton.html University of Pennsylvania Archival Collection]]
* [http://www.icasinc.org/bios/chance.html a long CV of Prof. Britton Chance]
* http://www.archives.upenn.edu/histy/people/1900s/chance_britton.html - A good biography of Britton Chance,PhD<sup>2</sup>
* http://www.icasinc.org/bios/chance.html - a long CV of Prof. Britton Chance

⚫
* [http://www.uphs.upenn.edu/biocbiop/faculty/pages/chance.html Academic home page]
* [http://www.jbc.org/cgi/content/full/279/50/e10 Kresge N, Simoni RD, Hill RL. Britton Chance: Olympian and Developer of Stop-Flow Methods. J. Biol. Chem., Vol. 279, Issue 50, 10, December 10, 2004.]
{{Winners of the National Medal of Science|biological}}
{{Winners of the National Medal of Science|biological}}


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| DATE OF BIRTH = July 24, 1913
| DATE OF BIRTH = July 24, 1913
| PLACE OF BIRTH = Wilkes-Barre, Pennsylvania
| PLACE OF BIRTH = Wilkes-Barre, Pennsylvania
| DATE OF DEATH = November 16, 2010
| DATE OF DEATH =
| PLACE OF DEATH = Philadelphia, Pennsylvania
| PLACE OF DEATH =
}}
}}
{{DEFAULTSORT:Chance, Britton}}
{{DEFAULTSORT:Chance, Britton}}
[[Category:1913 births]]
[[Category:1913 births]]
[[Category:2010 deaths]]
[[Category:Living people]]
[[Category:Alumni of the University of Cambridge]]
[[Category:Alumni of the University of Cambridge]]
[[Category:University of Pennsylvania alumni]]
[[Category:University of Pennsylvania alumni]]

Revision as of 05:55, 20 November 2010

Britton Chance
Born(1913-07-24)July 24, 1913
Wilkes-Barre, Pennsylvania
NationalityUnited States
Alma materUniversity of Pennsylvania
Cambridge University
Known forEnzyme kinetics
Optical imaging
MRI
Scientific career
FieldsBiophysics
Biochemistry
InstitutionsUniversity of Pennsylvania
Olympic medal record
Men's Sailing
Representing  United States
Gold medal – first place Helsinki 1952 5.5 metre class

Britton Chance (born July 24, 1913) is the Eldridge Reeves Johnson Professor Emeritus of Biochemistry and Biophysics, as well as Professor Emeritus of Physical Chemistry and Radiological Physics at the School of Medicine of the University of Pennsylvania. He was born in Wilkes-Barre, Pennsylvania. He received a B.A. (1935), M.A. (1936) and Ph.D. degree in Physical Chemistry 1940 at the University of Pennsylvania, where he was a member of St. Anthony Hall. He earned a second Ph.D. at Cambridge University in 1942 in Biology/Physiology. In 1952 he received his D.Sc. from Cambridge. His research interests focused on the use of infrared light to characterize the properties of various tissues and breast tumors. He joined the United States National Academy of Sciences in 1952. Chance received the National Medal of Science in 1974[1]. He was also previously elected a Foreign Member of the Royal Swedish Academy of Sciences, Medical Sciences, in 1968, as well as a Foreign Member of the Royal Society (London) in 1981.

During World War II, Chance worked for the Radiation Laboratory at the Massachusetts Institute of Technology which was working on the development of radar.

He won a gold medal for the United States at the 1952 Summer Olympics in the 5½ Meter Class, alongside Edgar White and Sumner White[2].

From 1995 he had been the President of the Medical Diagnostic Research Foundation (MDRF) in Philadelphia.[3]

ISOTT established The Britton Chance Award in honor of Professor Chance's long-standing commitment, interest and contributions to the science and engineering aspects of oxygen transport to tissue and to the society. This award was first presented in 2004 during the annual conference of ISOTT in Bari, Italy.[4]

Honorary degrees

  • MDs from: Karolinska Institute (in 1962), University of Düsseldorf (1991),University of Buenos Aires (1993), University of Copenhagen (1995), Universita Degli Studi Di Roma "Tor Vergata" (1997).
  • D.Sc. degrees from: Medical College of Ohio at Toledo in 1974, Semmelweis University in 1976, Hahnemann Medical College in 1977, University of Pennsylvania in 1985, University of Helsinki in 1990.

Awards

References

  1. ^ National Science Foundation - The President's National Medal of Science
  2. ^ http://www.ussailing.org/Olympics/usmedals.htm
  3. ^ http://www.archives.upenn.edu/people/1900s/chance_britton.html
  4. ^ http://www.isott.info/index.php?option=com_content&task=view&id=24&Itemid=67

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