Glia maturation factor

"GMFB" redirects here. For the television program that uses these initials, see Good Morning Football.

glia maturation factor, beta
Identifiers
Symbol	GMFB
NCBI gene	2764
HGNC	4373
OMIM	601713
RefSeq	NM_004124
UniProt	P60983
Other data
Locus	Chr. 14 q22.1
Search for Structures Swiss-model Domains InterPro

glia maturation factor, gamma
Identifiers
Symbol	GMFG
NCBI gene	9535
HGNC	4374
OMIM	604104
RefSeq	NM_004877
UniProt	O60234
Other data
Locus	Chr. 19 q13.2
Search for Structures Swiss-model Domains InterPro

Glia maturation factor is a neurotrophic factor implicated in nervous system development, angiogenesis and immune function. In humans, the glia maturation factor beta and glia maturation factor gamma proteins are encoded by the GMFB and GMFG genes, respectively.

The structures of mouse glia maturation factors beta and gamma, solved by both crystallography and NMR, reveal similarities and critical differences with ADF-H (actin depolymerization factor homology) domains and suggest new means of experimentally addressing the function of this protein family.

See also

Stereo ribbon diagram of the crystal structure of GMFG. Spectral coloring is from blue (N-terminus) to red (C-terminus). Secondary structural elements are indicated

• Glia+maturation+factor at the U.S. National Library of Medicine Medical Subject Headings (MeSH)