FGF6

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FGF6
Identifiers
Aliases FGF6, HBGF-6, HST2, fibroblast growth factor 6
External IDs MGI: 95520 HomoloGene: 10870 GeneCards: FGF6
Gene location (Human)
Chromosome 12 (human)
Chr. Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for FGF6
Genomic location for FGF6
Band 12p13.32 Start 4,428,155 bp[1]
End 4,445,614 bp[1]
RNA expression pattern
PBB GE FGF6 208417 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020996

NM_010204

RefSeq (protein)

NP_066276

NP_034334

Location (UCSC) Chr 12: 4.43 – 4.45 Mb Chr 12: 127.02 – 127.03 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Fibroblast growth factor 6 is a protein that in humans is encoded by the FGF6 gene.[5][6]

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation.[6]

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