FGF6

From Wikipedia, the free encyclopedia
Jump to: navigation, search
FGF6
Identifiers
Aliases FGF6, HBGF-6, HST2, fibroblast growth factor 6
External IDs MGI: 95520 HomoloGene: 10870 GeneCards: 2251
RNA expression pattern
PBB GE FGF6 208417 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020996

NM_010204

RefSeq (protein)

NP_066276.2

NP_034334.1

Location (UCSC) Chr 12: 4.43 – 4.45 Mb Chr 6: 127.02 – 127.03 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Fibroblast growth factor 6 is a protein that in humans is encoded by the FGF6 gene.[1][2]

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation.[2]

References[edit]

  1. ^ Zhang X, Ibrahimi OA, Olsen SK, Umemori H, Mohammadi M, Ornitz DM (Jun 2006). "Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family". J Biol Chem 281 (23): 15694–700. doi:10.1074/jbc.M601252200. PMC 2080618. PMID 16597617. 
  2. ^ a b "Entrez Gene: FGF6 fibroblast growth factor 6". 

Further reading[edit]