Duligotuzumab

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Duligotuzumab
Monoclonal antibody
Type Whole antibody
Source Human
Target HER3
Clinical data
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none

Duligotuzumab (INN) is a humanized IgG1 monoclonal antibody designed for the treatment of cancer. It acts as an immunomodulator and binds to HER3.[1] It is in development by Roche. Clinical development for head and neck cancer and colorectal cancer have been discontinued, but phase I trials in combination with cobimetinib are evaluating safety for treatment of solid tumors.[2]

References[edit]

  1. ^ World Health Organization (2012). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 107" (PDF). WHO Drug Information. 26 (2). 
  2. ^ "Duligotuzumab". AdisInsight.