Cefditoren

Cefditoren

Systematic (IUPAC) name
(7R)-7-((Z)-2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((Z)-2-(4-methylthiazol-5-yl)vinyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Clinical data
Trade names	Spectracef
AHFS/Drugs.com	monograph
MedlinePlus	a605003
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	104145-95-1 N
ATC code	J01DD16
PubChem	CID 9870843
DrugBank	DB01066
ChemSpider	8046534 Y
UNII	81QS09V3YW Y
KEGG	D07639 N
ChEBI	CHEBI:59343 Y
Chemical data
Formula	C19H18N6O5S3
Mol. mass	506.58 g/mol
SMILES O=C3N2/C(=C(/C=C\c1scnc1C)CS[C@@H]2[C@@H]3NC(=O)C(=N\OC)/c4nc(sc4)N)C(=O)O
InChI InChI=1S/C19H18N6O5S3/c1-8-11(33-7-21-8)4-3-9-5-31-17-13(16(27)25(17)14(9)18(28)29)23-15(26)12(24-30-2)10-6-32-19(20)22-10/h3-4,6-7,13,17H,5H2,1-2H3,(H2,20,22)(H,23,26)(H,28,29)/b4-3-,24-12-/t13-,17-/m1/s1 Y Key:KMIPKYQIOVAHOP-YLGJWRNMSA-N Y
N (what is this?)  (verify)

Cefditoren is a third-generation cephalosporin antibiotic for oral use. It is commonly marketed under the trade name Spectracef by Cornerstone BioPharma.

Cefditoren is also marketed under the name Meiact.

Clinical use

Main article: Cephalosporin

Indications

Cefditoren is used to treat uncomplicated skin and skin structure infections, community-acquired pneumonia, acute bacterial exacerbation of chronic bronchitis (ABECB), pharyngitis, and tonsillitis.

Formulations

Cefditoren is available as 200 and 400 mg tablets. It can be formulated as the prodrug cefditoren pivoxil.

Chemical structure of cefditoren pivoxil

External links

• Manufacturer's Product website
• Manufacturer's prescribing information for Spectracef