Cefradine

Cefradine

Systematic (IUPAC) name
(6R,7R)-7-{[(2R)-2-amino-2-(1-cyclohexa-1,4- dienyl)acetyl]amino}-3-methyl-8-oxo-5-thia- 1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Clinical data
AHFS/Drugs.com	International Drug Names
MedlinePlus	a601206
Pregnancy cat.	?
Legal status	℞ Prescription only
Routes	Oral, IM, IV
Pharmacokinetic data
Bioavailability	Well absorbed
Protein binding	<10%
Metabolism	Nil
Half-life	0.9 hours
Excretion	Renal, unchanged
Identifiers
CAS number	38821-53-3
ATC code	J01DB09
PubChem	CID 38103
DrugBank	DB01333
ChemSpider	34933 Y
UNII	9YA6SX5S4D Y
KEGG	D00264 Y
ChEBI	CHEBI:3547 Y
ChEMBL	CHEMBL1604 Y
Chemical data
Formula	C16H19N3O4S
Mol. mass	349.406 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C16H19N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1 Y Key:RDLPVSKMFDYCOR-UEKVPHQBSA-N Y
Y (what is this?)  (verify)

Cefradine (INN) (formerly cephradine BAN) is a first generation cephalosporin antibiotic.

Indications

It has similar spectrum of activity to cefalexin.

Formulations

Capsules containing 250 mg or 500 mg, Syrup containing 250 mg/5 ml, or vials for injection containing 500 mg or 1 g.

References

• British National Formulary 45 March 2003