Cefpirome

Cefpirome

Systematic (IUPAC) name
1-{[(6R,7R)-7-[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxylato-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-5H,6H,7H-cyclopenta[b]pyridin-1-ium
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	84957-29-9
ATC code	J01DE02
PubChem	CID 6917674
ChemSpider	23089536
UNII	S72Q2F09HY Y
KEGG	D07649 Y
Chemical data
Formula	C22H22N6O5S2
Mol. mass	514.58 g/mol
InChI InChI=1S/C22H22N6O5S2/c1-33-26-15(13-10-35-22(23)24-13)18(29)25-16-19(30)28-17(21(31)32)12(9-34-20(16)28)8-27-7-3-5-11-4-2-6-14(11)27/h3,5,7,10,16,20H,2,4,6,8-9H2,1H3,(H3-,23,24,25,29,31,32)/b26-15-/t16-,20+/m1/s1 Key:DKOQGJHPHLTOJR-XECLGWKCSA-N
Y (what is this?)  (verify)

Cefpirome is a fourth-generation cephalosporin. Trade names include Cefrom, Keiten, Broact, Cefir. Cefpirome is considered highly active against Gram-negative bacteria, including Pseudomonas aeruginosa, and Gram-positive bacteria. It is marketed under the brand name of CEFROM by sanofi aventis group india .

Spectrum of Bacterial Susceptibility and Resistance

Currently, Bacteroides fragilis, Enterococci, Pseudomonas spp. and Staphylococci are resistant to Cefpirome Sulfate, and some Haemophilus spp. and Pneumococci have developed resistance to Cefpirome Sulfate to varying degrees.