Extended-spectrum penicillin

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Extended-spectrum penicillin is a group of antibiotics that has the widest antibacterial spectrum of all penicillins.[1] It is also called antipseudomonal penicillins.[citation needed] This group includes the carboxypenicillins and the ureidopenicillins. Note that aminopenicillins, in contrast, do not have activity against Pseudomonas species, as their positively-charged amino group does not hinder degradation by bacterially-produced beta-lactamases. [2]

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  1. ^ Comprehensive Pharmacy Review, Leon Shargel, 6th edition, p917
  2. ^ Golan, David E. Principles of Pharmacology (2 ed.). Lippincott Williams & Wilkins. p. 610. ISBN 1608312704.