|Jmol-3D images||Image 1|
|Molar mass||213.23 g mol−1|
|Melting point||215 °C; 419 °F; 488 K (decomposes)|
| (what is: / ?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Kainic acid is a natural marine acid present in some seaweed. It is a specific agonist for the kainate receptor used as an ionotropic glutamate receptor which mimics the effect of glutamate. Along with quisqualate, it is used in experiments to distinguish a receptor from the other ionotropic receptors for glutamate such as NMDA and AMPA.
Kainic acid is a potent central nervous system stimulant, and has been developed as the prototype neuroexcitatory amino acid for the induction of seizures in experimental animals, at a typical dose of 10-30 mg/kg in mice. Kainic acid is neuroexcitotoxic and epileptogenic, acting through specific kainate receptors. Because of the supply shortage in 2000, the price of kainic acid has risen significantly.
- antiworming agent
- neuroscience research
- PubChem 10255
- Moloney, Mark G. (1998). "Excitatory amino acids". Natural Product Reports 15 (2): 205–219. doi:10.1039/a815205y. PMID 9586226.