Xanthurenic acid
From Wikipedia, the free encyclopedia
| Xanthurenic acid[1] | |
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8-Hydroxy-4-oxo-1H-quinoline-2-carboxylic acid |
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Other names
Xanthuric acid |
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| Identifiers | |
| CAS number | 59-00-7  |
| PubChem | 5699 |
| ChEBI | CHEBI:10072 |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C10H7NO4 |
| Molar mass | 205.17 g/mol |
| Appearance | Yellow crystals |
| Melting point |
286 °C, 559 K, 547 °F |
| Solubility in water | Insoluble |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Xanthurenic acid is a chemical shown to induce gametogenesis of Plasmodium falciparum, the parasite that causes malaria.[2] It is found in the gut of the Anopheles mosquito.
Xanthurenic acid is a metabolic intermediate that accumulates and is excreted by pyridoxine (vitamin B6) deficient animals after the ingestion of tryptophan.[1][3]
[edit] See also
[edit] References
- ^ a b Merck Index, 11th Edition, 9977.
- ^ Billker, O; Lindo, V; Panico, M; Etienne, AE; Paxton, T; Dell, A; Rogers, M; Sinden, RE et al. (March 19, 1998). "Identification of xanthurenic acid as the putative inducer of malaria development in the mosquito". Nature 392 (6673): 289–292. doi:10.1038/32667. PMID 9521324.
- ^ Xanthurenic acid at Sigma-Aldrich
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