RPS11

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Ribosomal protein S11
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols RPS11 ; S11
External IDs OMIM180471 MGI1351329 HomoloGene88443 GeneCards: RPS11 Gene
Orthologs
Species Human Mouse
Entrez 6205 27207
Ensembl ENSG00000142534 ENSMUSG00000003429
UniProt P62280 P62281
RefSeq (mRNA) NM_001015 NM_013725
RefSeq (protein) NP_001006 NP_038753
Location (UCSC) Chr 19:
50 – 50 Mb
Chr 7:
45.12 – 45.12 Mb
PubMed search [1] [2]

40S ribosomal protein S11 is a protein that in humans is encoded by the RPS11 gene.[1][2][3]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S17P family of ribosomal proteins. It is located in the cytoplasm. The gene product of the E. coli ortholog (ribosomal protein S17) is thought to be involved in the recognition of termination codons. This gene is co-transcribed with a small nucleolar RNA gene, which is located in its third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[3]

References[edit]

  1. ^ Feo S, Davies B, Fried M (Jun 1992). "The mapping of seven intron-containing ribosomal protein genes shows they are unlinked in the human genome". Genomics 13 (1): 201–7. doi:10.1016/0888-7543(92)90221-D. PMID 1577483. 
  2. ^ Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (Aug 1998). "A map of 75 human ribosomal protein genes". Genome Res 8 (5): 509–23. doi:10.1101/gr.8.5.509. PMID 9582194. 
  3. ^ a b "Entrez Gene: RPS11 ribosomal protein S11". 

Further reading[edit]