GFRα
From Wikipedia, the free encyclopedia
This is the current revision of this page, as edited by OAbot (talk | contribs) at 02:58, 6 July 2021 (Open access bot: doi added to citation with #oabot.). The present address (URL) is a permanent link to this version.
Revision as of 02:58, 6 July 2021 by OAbot (talk | contribs) (Open access bot: doi added to citation with #oabot.)
(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff)
| Glial cell line-derived neurotrophic factor receptor | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | GFRα | ||||||||
| Pfam | PF02351 | ||||||||
| InterPro | IPR003438 | ||||||||
| Membranome | 44 | ||||||||
| |||||||||
The GDNF family receptor-α (GFRα) proteins are a group of co-receptors which form complexes with GDNF-family ligands (GFLs) to activate RET, the receptor of the GFLs.[1] The GFRα co-receptors include the following:
- GFRα1 – preference for GDNF
- GFRα2 – preference for neurturin
- GFRα3 – preference for artemin
- GFRα4 – preference for persephin
- GFRAL - receptor for GDF15
References
[edit]- ^ Enokido Y, de Sauvage F, Hongo JA, Ninkina N, Rosenthal A, Buchman VL, Davies AM (September 1998). "GFR alpha-4 and the tyrosine kinase Ret form a functional receptor complex for persephin". Current Biology. 8 (18): 1019–22. doi:10.1016/s0960-9822(07)00422-8. PMID 9740802. S2CID 1669891.
| Neurotrophins | |
|---|---|
| GDNF family | |
| Ephrins | |
| CNTF family | |
| Other | |
.svg){kind=small} | This biochemistry article is a stub. You can help Wikipedia by expanding it. |
Retrieved from "https://en.wikipedia.org/w/index.php?title=GFRα&oldid=1032207502"