14-Ethoxymetopon

14-Ethoxymetopon
Clinical data
Other names	14-Ethoxymetopon
Identifiers
	IUPAC name 3-hydroxy- 14-ethoxy- 5-methyl- 7,8-dihydro- 4,5α-epoxy- 17-methylmorphinan- 6-one;
CAS Number	131575-04-7 ;
PubChem CID	5487378;
ChemSpider	4589341 ;
CompTox Dashboard (EPA)	DTXSID50157119 ;
Chemical and physical data
Formula	C20H25NO4
Molar mass	343.42 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCOC12CCC(=O)[C@@]3(C14CCN([C@@H]2CC5=C4C(=C(C=C5)O)O3)C)C;
	InChI InChI=1S/C20H25NO4/c1-4-24-20-8-7-15(23)18(2)19(20)9-10-21(3)14(20)11-12-5-6-13(22)17(25-18)16(12)19/h5-6,14,22H,4,7-11H2,1-3H3/t14-,18-,19?,20?/m1/s1 ; Key:LDTUYTORBPKTNO-HPJZBDCMSA-N ;
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14-Ethoxymetopon^[1] is an opiate analogue that is a derivative of metopon which has been substituted with an ethoxy group at the 14-position. It is a highly potent analgesic drug several hundred times stronger than morphine.^[2]

References

^ US Patent 6476044
^ Fürst, Z; Búzás, B; Friedmann, T; Schmidhammer, H; Borsodi, A (1993). "Highly potent novel opioid receptor agonist in the 14-alkoxymetopon series". European Journal of Pharmacology. 236 (2): 209–15. doi:10.1016/0014-2999(93)90591-5. PMID 8391457.

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[1] US Patent 6476044

[2] Fürst, Z; Búzás, B; Friedmann, T; Schmidhammer, H; Borsodi, A (1993). "Highly potent novel opioid receptor agonist in the 14-alkoxymetopon series". European Journal of Pharmacology. 236 (2): 209–15. doi:10.1016/0014-2999(93)90591-5. PMID 8391457.

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