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TRIMU 5

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TRIMU 5
Names
IUPAC name
L-tyrosyl-N-{[(3-methylbutyl)amino]acetyl}-D-alaninamide
Other names
(2S)-2-amino-3-(4-hydroxyphenyl)-N-[(2R)-1-{[2-(3-methylbutylamino)acetyl]amino}-1-oxopropan-2-yl]propanamide
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C19H30N4O4/c1-12(2)8-9-21-11-17(25)23-18(26)13(3)22-19(27)16(20)10-14-4-6-15(24)7-5-14/h4-7,12-13,16,21,24H,8-11,20H2,1-3H3,(H,22,27)(H,23,25,26)/t13-,16?/m1/s1 checkY
    Key: QOGVSHVPIMZZRN-JBZHPUCOSA-N checkY
  • InChI=1/C19H30N4O4/c1-12(2)8-9-21-11-17(25)23-18(26)13(3)22-19(27)16(20)10-14-4-6-15(24)7-5-14/h4-7,12-13,16,21,24H,8-11,20H2,1-3H3,(H,22,27)(H,23,25,26)/t13-,16?/m1/s1
    Key: QOGVSHVPIMZZRN-JBZHPUCOBN
  • Oc1ccc(C[C@@H](N)C(=O)N[C@H](C)C(=O)NC(=O)CNCCC(C)C)cc1
Properties
C19H30N4O4
Molar mass 378.466
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

TRIMU 5 is a selective agonist of the mu opioid receptor type 2.[1]

References

  1. ^ Eisenberg RM (1994). "TRIMU-5, a mu 2-opioid receptor agonist, stimulates the hypothalamo-pituitary-adrenal axis". Pharmacol. Biochem. Behav. 47 (4): 943–6. doi:10.1016/0091-3057(94)90300-X. PMID 8029266.