Diampromide

Diampromide
Clinical data
Other names	Diampromide
ATC code	none;
Legal status
Legal status	AU: S9 (Prohibited substance); CA: Schedule I; DE: Anlage I (Authorized scientific use only); US: Schedule I; UN: Psychotropic Schedule I;
Identifiers
	IUPAC name N-[2-(methyl-(2-phenylethyl)amino)propyl]-N-phenylpropanamide;
CAS Number	552-25-0;
PubChem CID	62370;
DrugBank	DB01502 ;
ChemSpider	56158 ;
UNII	26G7YC77BU;
ChEMBL	ChEMBL2106220;
CompTox Dashboard (EPA)	DTXSID70862177 ;
Chemical and physical data
Formula	C21H28N2O
Molar mass	324.46 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC(=O)N(CC(C)N(C)CCc1ccccc1)c1ccccc1;
	InChI InChI=1S/C21H28N2O/c1-4-21(24)23(20-13-9-6-10-14-20)17-18(2)22(3)16-15-19-11-7-5-8-12-19/h5-14,18H,4,15-17H2,1-3H3 ; Key:RXTHKWVSXOIHJS-UHFFFAOYSA-N ;
	(verify)

Diampromide is an opioid analgesic from the ampromide family of drugs, related to other drugs such as propiram. It was invented in the 1960s by American Cyanamid,^[1] and can be described as a ring-opened analogue of fentanyl.[1]

Diampromide produces similar effects to other opioids, including analgesia, sedation, dizziness and nausea, and is around the same potency as morphine.^[2]

Diampromide is in Schedule I of the Controlled Substances Act 1970 of the United States as a Narcotic with ACSCN 9615 with a zero aggregate manufacturing quota as of 2014. ^[3] It is listed under the Single Convention for the Control of Narcotic Substances 1961 and is controlled in most countries in the same fashion as is morphine.

References

^ US Patent 2944081
^ Ivanovic MD, Micovic IV, Vuckovic S, Prostran M, Todorovic Z, Ivanovic ER, Kiricojevic VD, Djordjevic JB, Dosen-Micovic LJ. The synthesis and pharmacological evaluation of 2,3-seco-fentanyl analogues. Journal of the Serbian Chemical Society. 2004; 69(11): 955-968.
^ http://www.deadiversion.usdoj.gov/fed_regs/quotas/2014/fr0825.htm

This analgesic-related article is a stub. You can help Wikipedia by expanding it.

[1] US Patent 2944081

[2] Ivanovic MD, Micovic IV, Vuckovic S, Prostran M, Todorovic Z, Ivanovic ER, Kiricojevic VD, Djordjevic JB, Dosen-Micovic LJ. The synthesis and pharmacological evaluation of 2,3-seco-fentanyl analogues. Journal of the Serbian Chemical Society. 2004; 69(11): 955-968.

[3] ttp://www.deadiversion.usdoj.gov/fed_regs/quotas/2014/fr0825.htm

[1]

[2]

[3]