Ephrin A4

EFNA4
Identifiers
Aliases	EFNA4, EFL4, EPLG4, LERK4, ephrin A4, LERK-4
External IDs	OMIM: 601380 MGI: 106643 HomoloGene: 3830 GeneCards: EFNA4
Gene location (Human)
Chr.	Chromosome 1 (human)
End	155,069,553 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	89,245,335 bp
RNA expression pattern
	Top expressed in
	skin of abdomen; ; rectum; ; left adrenal gland; ; minor salivary glands; ; stromal cell of endometrium; ; vagina; ; right lobe of liver; ; monocyte; ; vulva; ; canal of the cervix;
	Top expressed in
	maxillary prominence; ; lip; ; superior surface of tongue; ; hand; ; saccule; ; abdominal wall; ; somite; ; otic placode; ; secondary oocyte; ; ganglionic eminence;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transmembrane-ephrin receptor activity; protein binding; ephrin receptor binding;
Cellular component	anchored component of membrane; plasma membrane; integral component of plasma membrane; membrane; extracellular region; intrinsic component of plasma membrane;
Biological process	cell-cell signaling; ephrin receptor signaling pathway; axon guidance; osteoclast differentiation; bone remodeling;
	Sources:Amigo / QuickGO
Orthologs
	1945
	13639
	ENSG00000243364
	ENSMUSG00000028040
	P52798
	O08542
	NM_182690; NM_005227; NM_182689
	NM_007910
	NP_005218; NP_872631; NP_872632
	NP_031936
	Wikidata
View/Edit Human	View/Edit Mouse

Ephrin A4 is a protein that in humans is encoded by the EFNA4 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000243364 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028040 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Cerretti DP, Lyman SD, Kozlosky CJ, Copeland NG, Gilbert DJ, Jenkins NA, Valentine V, Kirstein MN, Shapiro DN, Morris SW (Jan 1997). "The genes encoding the eph-related receptor tyrosine kinase ligands LERK-1 (EPLG1, Epl1), LERK-3 (EPLG3, Epl3), and LERK-4 (EPLG4, Epl4) are clustered on human chromosome 1 and mouse chromosome 3". Genomics. 33 (2): 277–82. doi:10.1006/geno.1996.0192. PMID 8660976.
^ "Entrez Gene: EFNA4 ephrin-A4".

v t e Intercellular signaling peptides and proteins / ligands
Growth factors	Epidermal growth factor Fibroblast growth factor Nerve growth factor Platelet-derived growth factor Transforming growth factor beta superfamily Vascular endothelial growth factor
Ephrin	EFNA1 EFNA2 EFNA3 EFNA4 EFNA5 EFNB1 EFNB2 EFNB3
Other	Adipokine Agouti signaling protein Agouti-related protein Angiogenic protein CCN intercellular signaling protein Cysteine-rich protein 61 Connective tissue growth factor Nephroblastoma overexpressed protein Cytokine Endothelin EDN1 EDN2 EDN3 Hedgehog protein Interferon Kinin Parathyroid hormone-related protein Semaphorin Somatomedin Tolloid-like metalloproteinase Tumor necrosis factor Wnt protein
see also extracellular ligand disorders