Mebhydrolin

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Mebhydrolin
Clinical data
Other names9-Benzyl-2-methyl-2,3,4,9-tetrahydro-1H-gamma-carboline, Incidal, Omeril, Diazolin, Fabahistin, mebhydrolin napadisylate, mebhydroline 1,5-naphthalenedisulfonate[1]
AHFS/Drugs.comInternational Drug Names
Pregnancy
category
  • Not established[2]
Routes of
administration
Oral[2]
ATC code
Identifiers
  • 5-benzyl-2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indole
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.007.606 Edit this at Wikidata
Chemical and physical data
FormulaC19H20N2[4]
Molar mass276.376 g/mol g·mol−1
3D model (JSmol)
  • CN3Cc4c1ccccc1n(Cc2ccccc2)c4CC3
  • InChI=1S/C19H20N2/c1-20-12-11-19-17(14-20)16-9-5-6-10-18(16)21(19)13-15-7-3-2-4-8-15/h2-10H,11-14H2,1H3 checkY
  • Key:FQQIIPAOSKSOJM-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Mebhydrolin (INN) or mebhydroline is an antihistamine. It is not available in the United States, but it is in various other countries under the brand names Bexidal (BD) and Diazolin (RU). It is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.

Mebhydrolin has been shown to magnify the performance-deficit effects of alcohol.[5]

References

  1. ^ "Mebhydroline". National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Retrieved 2007-03-02.
  2. ^ a b "FABAHISTIN 50 mg (Tablets)". South African Electronic Package Inserts. September 1970. Archived from the original on October 17, 2006. Retrieved 2007-03-02. {{cite web}}: Unknown parameter |deadurl= ignored (|url-status= suggested) (help)
  3. ^ "Diazoline". National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Retrieved 2007-03-02.
  4. ^ "Mebhydrolin chemical information". PubChem. Retrieved 2007-03-02.
  5. ^ Franks HM, Lawrie M, Schabinsky VV, Starmer GA, Teo RK (October 1981). "Interaction between ethanol and antihistamines: 3. mebhydrolin". Med. J. Aust. 2 (9): 477–9. PMID 6119605.