Pyrrolidinylthiambutene

Pyrrolidinylthiambutene
Clinical data
ATC code	none;
Identifiers
	IUPAC name 1-(1-methyl-3,3-di-2-thienylprop-2-en-1-yl)pyrrolidine;
CAS Number	785722-57-8;
Chemical and physical data
Formula	C16H19NS2
Molar mass	289.458 g/mol g·mol−1
3D model (JSmol)	Interactive image;
Melting point	167 to 169 °C (333 to 336 °F)
	SMILES C2CCCN2C(C)C=C(c1sccc1)c3sccc3;
	(verify)

Pyrrolidinylthiambutene is an opioid analgesic drug from the thiambutene family with around 3/4 of the potency of morphine.^[1]^[2]^[3] It would be considered an illegal controlled substance analogue in some countries such as the USA, Australia and New Zealand, but is legal in countries not possessing a controlled-substances-analog-act equivalent.

References

^ Adamson DW, Green AF. A new series of analgesics. Nature. 1950 Jan 21;165(4186):122. doi:10.1038/165122a0 PMID 15409854
^ Adamson DW, Duffin WM, Green AF. Dithienylbutylamines as analgesics. Nature. 1951 Jan 27;167(4239):153-4. doi:10.1038/167153b0 PMID 14806409
^ Green AF. Analgesic and other properties of 3: 3-dithienylalkenylamines. British Journal of Pharmacology and Chemotherapy. 1953 Mar;8(1):2-9. PMID 13066683

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[1] Adamson DW, Green AF. A new series of analgesics. Nature. 1950 Jan 21;165(4186):122. doi:10.1038/165122a0 PMID 15409854

[2] Adamson DW, Duffin WM, Green AF. Dithienylbutylamines as analgesics. Nature. 1951 Jan 27;167(4239):153-4. doi:10.1038/167153b0 PMID 14806409

[3] Green AF. Analgesic and other properties of 3: 3-dithienylalkenylamines. British Journal of Pharmacology and Chemotherapy. 1953 Mar;8(1):2-9. PMID 13066683

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