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DPI-287

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DPI-287
Identifiers
  • 4-[(R)-[(2S,5R)-2,5-dimethyl-4-benzylpiperazin-1-yl]-(3-hydroxyphenyl)methyl]-N,N-diethylbenzamide
PubChem CID
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC31H39N3O2
Molar mass485.672 g·mol−1
3D model (JSmol)
  • CCN(CC)C(=O)c2ccc(cc2)C(c(ccc4)cc4O)N(CC1C)C(C)CN1Cc3ccccc3
  (verify)

DPI-287 is an opioid drug that is used in scientific research. It is a highly selective agonist for the δ-opioid receptor, which produces less convulsions than most drugs from this family.[1] It has antidepressant-like effects.[2]

References

  1. ^ Jutkiewicz EM (June 2006). "The antidepressant-like effects of delta-opioid receptor agonists". Molecular Interventions. 6 (3): 162–9. doi:10.1124/mi.6.3.7. PMID 16809477.
  2. ^ Jutkiewicz EM, Chang KJ, Rice KC, Woods JH (2005). "Characterization of a novel nonpeptide delta-opioid agonist analog DPI287 with antidepressant-like activity". Experimental Biology Meeting Abstracts (Abstract # 874.4).
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