Metethoheptazine

Metethoheptazine
Clinical data
Other names	WY-535
ATC code	none;
Identifiers
	IUPAC name ethyl 1,3-dimethyl-4-phenylazepane-4-carboxylate;
CAS Number	509-84-2 ;
PubChem CID	176888;
ChemSpider	154060 ;
UNII	S36J5ZY2TH;
Chemical and physical data
Formula	C17H25NO2
Molar mass	275.392 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(OCC)C2(c1ccccc1)CCCN(C)CC2C;
	InChI InChI=1S/C17H25NO2/c1-4-20-16(19)17(15-9-6-5-7-10-15)11-8-12-18(3)13-14(17)2/h5-7,9-10,14H,4,8,11-13H2,1-3H3 ; Key:BOSULDNQDJLKKL-UHFFFAOYSA-N ;
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Metethoheptazine^[1] (WY-535) is an opioid analgesic from the phenazepine family. It was invented in the 1960s.^[2]

Metethoheptazine produces similar effects to other opioids, including analgesia, sedation, dizziness and nausea.

Metethoheptazine is not listed as a controlled substance under the Controlled Substances Act 1970 in the United States.^[3] The Canadian Controlled Drugs and Substances Act specifically excludes the phenazepine opioids from control.

References

^ GB Patent 843924
^ Walkenstein SS, Corradino RA, Wiser R, Gudmundsen CH. Metabolism of the Non-Narcotic Analgesic, WY-535. Biochemical Pharmacology. 1965 Feb;14:121-8.
^ "Conversion Factors for Controlled Substances". U.S. Department of Justice Drug Enforcement Administration. Retrieved 8 October 2018.

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[1] GB Patent 843924

[2] Walkenstein SS, Corradino RA, Wiser R, Gudmundsen CH. Metabolism of the Non-Narcotic Analgesic, WY-535. Biochemical Pharmacology. 1965 Feb;14:121-8.

[3] "Conversion Factors for Controlled Substances". U.S. Department of Justice Drug Enforcement Administration. Retrieved 8 October 2018.

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