Ephrin A3

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EFNA3
Identifiers
Aliases EFNA3, EFL2, EPLG3, Ehk1-L, LERK3, ephrin A3
External IDs MGI: 106644 HomoloGene: 3635 GeneCards: 1944
RNA expression pattern
PBB GE EFNA3 210132 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004952

NM_010108

RefSeq (protein)

NP_004943.1

NP_034238.1

Location (UCSC) Chr 1: 155.08 – 155.09 Mb Chr 3: 89.31 – 89.32 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Ephrin A3 is a protein that in humans is encoded by the EFNA3 gene.[3][4]

This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Cerretti DP, Lyman SD, Kozlosky CJ, Copeland NG, Gilbert DJ, Jenkins NA, Valentine V, Kirstein MN, Shapiro DN, Morris SW (Jan 1997). "The genes encoding the eph-related receptor tyrosine kinase ligands LERK-1 (EPLG1, Epl1), LERK-3 (EPLG3, Epl3), and LERK-4 (EPLG4, Epl4) are clustered on human chromosome 1 and mouse chromosome 3". Genomics. 33 (2): 277–82. doi:10.1006/geno.1996.0192. PMID 8660976. 
  4. ^ a b "Entrez Gene: EFNA3 ephrin-A3". 

Further reading[edit]