Ephrin A3

EFNA3
Identifiers
Aliases	EFNA3, EFL2, EPLG3, Ehk1-L, LERK3, ephrin A3
External IDs	OMIM: 601381; MGI: 106644; HomoloGene: 3635; GeneCards: EFNA3; OMA:EFNA3 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	155,087,538 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	89,322,965 bp
RNA expression pattern
	Top expressed in
	skin of leg; ; skin of abdomen; ; skin of arm; ; hair follicle; ; Region I of hippocampus proper; ; cervix epithelium; ; orbitofrontal cortex; ; prefrontal cortex; ; parotid gland; ; nucleus accumbens;
	Top expressed in
	lip; ; perirhinal cortex; ; entorhinal cortex; ; chorion; ; nasal epithelium; ; olfactory epithelium; ; subiculum; ; skin of external ear; ; dentate gyrus of hippocampal formation granule cell; ; esophagus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transmembrane-ephrin receptor activity; protein binding; ephrin receptor binding;
Cellular component	anchored component of membrane; plasma membrane; integral component of plasma membrane; membrane; intrinsic component of plasma membrane;
Biological process	cell-cell signaling; ephrin receptor signaling pathway; axon guidance; negative regulation of angiogenesis; regulation of neuron differentiation; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	1944
	13638
	ENSG00000143590
	ENSMUSG00000028039
	P52797
	O08545
	NM_004952
	NM_010108
	NP_004943
NP_034238; NP_001364045; NP_001364046; NP_001364047; NP_001364048;
	NP_001364049; NP_001364050
	Wikidata
View/Edit Human	View/Edit Mouse

Ephrin A3 is a protein that in humans is encoded by the EFNA3 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000143590 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028039 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Cerretti DP, Lyman SD, Kozlosky CJ, Copeland NG, Gilbert DJ, Jenkins NA, Valentine V, Kirstein MN, Shapiro DN, Morris SW (Jan 1997). "The genes encoding the eph-related receptor tyrosine kinase ligands LERK-1 (EPLG1, Epl1), LERK-3 (EPLG3, Epl3), and LERK-4 (EPLG4, Epl4) are clustered on human chromosome 1 and mouse chromosome 3". Genomics. 33 (2): 277–82. doi:10.1006/geno.1996.0192. PMID 8660976.
^ "Entrez Gene: EFNA3 ephrin-A3".

v t e Intercellular signaling peptides and proteins / ligands
Growth factors	Epidermal growth factor Fibroblast growth factor Nerve growth factor Platelet-derived growth factor Transforming growth factor beta superfamily Vascular endothelial growth factor
Ephrin	EFNA1 EFNA2 EFNA3 EFNA4 EFNA5 EFNB1 EFNB2 EFNB3
Other	Adipokine Agouti signaling protein Agouti-related protein Angiogenic protein CCN intercellular signaling protein Cysteine-rich protein 61 Connective tissue growth factor Nephroblastoma overexpressed protein Cytokine Endothelin EDN1 EDN2 EDN3 Hedgehog protein Interferon Kinin Parathyroid hormone-related protein Semaphorin Somatomedin Tolloid-like metalloproteinase Tumor necrosis factor Wnt protein
see also extracellular ligand disorders

References

Further reading