FGF14

FGF14
Identifiers
Aliases	FGF14, FGF-14, FHF-4, FHF4, SCA27, fibroblast growth factor 14
External IDs	OMIM: 601515 MGI: 109189 HomoloGene: 3037 GeneCards: FGF14
Gene location (Human)
Chr.	Chromosome 13 (human)
End	102,402,457 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	124,914,539 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; middle temporal gyrus; ; bronchial epithelial cell; ; Brodmann area 23; ; cerebellar vermis; ; endothelial cell; ; postcentral gyrus; ; superior frontal gyrus; ; entorhinal cortex; ; cerebellar hemisphere;
	Top expressed in
	barrel cortex; ; cerebellar vermis; ; olfactory tubercle; ; mammillary body; ; superior frontal gyrus; ; suprachiasmatic nucleus; ; supraoptic nucleus; ; nucleus accumbens; ; ventromedial nucleus; ; aortic valve;
	More reference expression data
	n/a
Gene ontology
Molecular function	fibroblast growth factor receptor binding; growth factor activity; heparin binding; protein binding;
Cellular component	extracellular region; nucleus; intracellular anatomical structure;
Biological process	regulation of synaptic vesicle recycling; JNK cascade; cell-cell signaling; fibroblast growth factor receptor signaling pathway; regulation of postsynaptic membrane potential; signal transduction; nervous system development; regulation of synaptic plasticity; positive regulation of high voltage-gated calcium channel activity; regulation of signaling receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	2259
	14169
	ENSG00000102466
	ENSMUSG00000025551
	Q92915
	P70379
NM_004115; NM_175929; NM_001321931; NM_001321932; NM_001321933;
	NM_001321934; NM_001321935; NM_001321936; NM_001321937; NM_001321938; NM_001321939; NM_001321940; NM_001321941; NM_001321942; NM_001321943; NM_001321944; NM_001321945; NM_001321946; NM_001321947; NM_001321948; NM_001321949; NM_001379342
	NM_010201; NM_207667
NP_001308860; NP_001308861; NP_001308862; NP_001308863; NP_001308864;
	NP_001308865; NP_001308866; NP_001308867; NP_001308868; NP_001308869; NP_001308870; NP_001308871; NP_001308872; NP_001308873; NP_001308874; NP_001308875; NP_001308876; NP_001308877; NP_001308878; NP_004106; NP_787125; NP_001366271
	NP_034331; NP_997550
	Wikidata
View/Edit Human	View/Edit Mouse

Fibroblast growth factor 14 is a protein that in humans is encoded by the FGF14 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000102466 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025551 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Smallwood PM, Munoz-Sanjuan I, Tong P, Macke JP, Hendry SH, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J (Oct 1996). "Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development". Proc Natl Acad Sci U S A. 93 (18): 9850–7. doi:10.1073/pnas.93.18.9850. PMC 38518. PMID 8790420.
^ Wozniak DF, Xiao M, Xu L, Yamada KA, Ornitz DM (Mar 2007). "Impaired spatial learning and defective theta burst induced LTP in mice lacking fibroblast growth factor 14". Neurobiol Dis. 26 (1): 14–26. doi:10.1016/j.nbd.2006.11.014. PMC 2267915. PMID 17236779.
^ "Entrez Gene: FGF14 fibroblast growth factor 14".

References

Further reading