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NPR2

From Wikipedia, the free encyclopedia
NPR2
Identifiers
AliasesNPR2, AMDM, ANPRB, ANPb, ECDM, GUC2B, GUCY2B, NPRB, NPRBi, SNSK, natriuretic peptide receptor 2, GCB, AMD1, GC-B
External IDsOMIM: 108961; MGI: 97372; HomoloGene: 2970; GeneCards: NPR2; OMA:NPR2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000907
NM_003995
NM_001378923

NM_173788
NM_001355466

RefSeq (protein)

NP_003986
NP_001365852

NP_776149
NP_001342395

Location (UCSC)Chr 9: 35.79 – 35.81 MbChr 4: 43.63 – 43.65 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Natriuretic peptide receptor B (NPR2), also known as atrionatriuretic peptide receptor B and formerly as guanylate cyclase B, is an atrial natriuretic peptide receptor which in humans is encoded by the NPR2 gene.[5]

A mutation in the NPR2 gene can result in achondroplasia and disproportionate dwarfism with short limbs.[6]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000159899Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028469Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: NPR2 natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)".
  6. ^ Tsuji T, Kunieda T (April 2005). "A loss-of-function mutation in natriuretic peptide receptor 2 (Npr2) gene is responsible for disproportionate dwarfism in cn/cn mouse". The Journal of Biological Chemistry. 280 (14): 14288–92. doi:10.1074/jbc.C500024200. PMID 15722353.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.