From Wikipedia, the free encyclopedia
Jump to: navigation, search
Clinical data
ATC code
  • none
CAS Number
PubChem CID
Chemical and physical data
Formula C15H21NO2
Molar mass 247.333 g/mol
3D model (Jmol)

Prodilidine is an opioid analgesic which is a ring-contracted analogue of prodine. It has around the same analgesic efficacy as codeine, but is only around 1/3 the potency (100mg prodilidine is equivalent to 3mg oral morphine). It has little abuse potential.[1][2][3][4][5]

See also[edit]


  1. ^ Fraser HF. Addictiveness of 1,2-dimethyl,3-phenyl,3-propionoxy pyrrolidine hydrochloride (ARC I-O-1) UNODC Bulletin on Narcotics 1964 Issue 1.
  2. ^ Splitter SR. Treatment of pain in patients with a new nonnarcotic analgesic, prodilidine hydrochloride (Cogesic). Current Therapeutic Research, Clinical and Experimental. 1961 Nov;3:472-7. PMID 13915874
  3. ^ Kissel JW, Albert JR, Boxill GC. The pharmacology of prodilidine hydrochloride, a new analgetic agent. Journal of Pharmacology and Experimental Therapeutics. 1961 Dec;134:332-40. PMID 14456453
  4. ^ Weikel JH Jr, Labudde JA. Absorption, excretion and fate of prodilidine. Journal of Pharmacology and Experimental Therapeutics. 1962 Dec;138:392-8. PMID 13999550
  5. ^ Batterman RC, Mouratoff GJ, Kaufman JE. Prodilidine Hydrochloride: A new moderately potent analgesic. American Journal of the Medical Sciences. 1964 Jan;247:62-8. PMID 14106881