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The rubiscolins are a group of opioid peptides that are formed during digestion of the ribulose bisphosphate carboxylase/oxygenase (Rubisco) protein from spinach leaves. Rubiscolins mimic the effects of opiates and, therefore, influence the brain. These peptides have much in common with the better-known gluten exorphins.
There are 2 known rubiscolins with known structure:
- Structure: H-Tyr-Pro-Leu-Asp-Leu-OH
- Structure: H-Tyr-Pro-Leu-Asp-Leu-Phe-OH
- rubiscolin-5 at the US National Library of Medicine Medical Subject Headings (MeSH)
- rubiscolin-6 at the US National Library of Medicine Medical Subject Headings (MeSH)
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