Papaveretum
This is an old revision of this page, as edited by Ponyo (talk | contribs) at 23:36, 13 February 2020 (Reverted edits by 166.255.148.3 (talk) to last version by IznoRepeat). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.
Combination of | |
---|---|
Morphine | Opioid analgesic |
Papaverine | Antispasmodic |
Codeine | Opioid analgesic |
Clinical data | |
Trade names | Omnopon |
ATC code | |
Identifiers | |
PubChem CID |
Papaveretum (BAN) is a preparation containing a mixture of hydrochloride salts of opium alkaloids. Since 1993, papaveretum has been defined in the British Pharmacopoeia (BP) as a mixture of 253 parts morphine hydrochloride, 23 parts papaverine hydrochloride, and 20 parts codeine hydrochloride.[1] It is commonly marketed to medical agencies under the trade name Omnopon.
Although the use of papaveretum is now relatively uncommon following the wide availability of single-component opiates and synthetic opioids (e.g. pethidine) it is still used to relieve moderate to severe pain and for pre-operative sedation. In clinical settings, papaveretum is usually administered to patients via subcutaneous, intramuscular or intravenous routes. Additionally, the morphine syrettes found in combat medical kits issued to military personnel actually contain omnopon.
Prior to 1993, papaveretum also contained noscapine, though this component was removed from the BP formulation due to the genotoxic potential of noscapine.
References
- ^ Sean C. Sweetman, ed. (November 30, 2004). Martindale: The complete drug reference (34th ed.). London: Pharmaceutical Press. ISBN 0-85369-550-4.
- Chemical articles without CAS registry number
- Articles without EBI source
- Chemical pages without ChemSpiderID
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Articles without InChI source
- Articles without UNII source
- Drugs with no legal status
- Articles containing unverified chemical infoboxes
- Drugs that are a combination of chemicals