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DUSP15

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DUSP15
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesDUSP15, VHY, C20orf57, dual specificity phosphatase 15
External IDsOMIM: 616776; MGI: 1934928; HomoloGene: 33586; GeneCards: DUSP15; OMA:DUSP15 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_177991
NM_001012644
NM_080611
NM_001320478
NM_001320479

NM_001159376
NM_145744

RefSeq (protein)

NP_001012662
NP_001307407
NP_001307408
NP_542178
NP_817130

NP_001152848
NP_665687

Location (UCSC)Chr 20: 31.85 – 31.87 MbChr 2: 152.78 – 152.79 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Dual specificity protein phosphatase 15 is an enzyme that in humans is encoded by the DUSP15 gene.[5][6]

The protein encoded by this gene belongs to the non-receptor class of the protein-tyrosine phosphatase family. The encoded protein has both protein-tyrosine phosphatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase. Three transcript variants, encoding two different isoforms have been found for this gene.[6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000149599Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042662Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Alonso A, Narisawa S, Bogetz J, Tautz L, Hadzic R, Huynh H, Williams S, Gjorloff-Wingren A, Bremer MC, Holsinger LJ, Millan JL, Mustelin T (Jul 2004). "VHY, a novel myristoylated testis-restricted dual specificity protein phosphatase related to VHX". J Biol Chem. 279 (31): 32586–91. doi:10.1074/jbc.M403442200. PMID 15138252.
  6. ^ a b "Entrez Gene: DUSP15 dual specificity phosphatase 15".

Further reading

  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Dual specificity protein phosphatase 15