Butaclamol
Appearance
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Revision as of 02:57, 16 May 2018 by OrganoMetallurgy (talk | contribs) (added Category:Tert-butyl compounds using HotCat)
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Formula | C25H31NO |
Molar mass | 361.52 g/mol g·mol−1 |
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Butaclamol (AY-23,028) is a typical antipsychotic which was never marketed.[1] Sold as the hydrochloride salt for use in research, the compound acts as a dopamine receptor antagonist.[2]
Chemistry
pKa = 7.15 (uncorrected for ionic strength)[3]
References
- ^ Buckingham, J (1985). Dictionary of organic compounds - Google Books. ISBN 9780412540905.
- ^ http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5=SEARCH_CONCAT_PNO%7CBRAND_KEY&N4=D033%7CSIGMA&N25=0&QS=ON&F=SPEC
- ^ F. A. Chrzanowski, B. A. McGrogan, B. E. Maryanoff (1985). "The pKa of butaclamol and the mode of butaclamol binding to central dopamine receptors." J. Med. Chem. 28 399-400.
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See also: Receptor/signaling modulators |
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Antidepressants (Tricyclic antidepressants (TCAs)) |
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Antihistamines |
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Antipsychotics |
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