PTP4A3

PTP4A3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1R6H, 1V3A, 2MBC
Identifiers
Aliases	PTP4A3, PRL-3, PRL-R, PRL3, protein tyrosine phosphatase type IVA, member 3, protein tyrosine phosphatase 4A3
External IDs	OMIM: 606449; MGI: 1277098; HomoloGene: 22500; GeneCards: PTP4A3; OMA:PTP4A3 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	141,432,454 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	73,630,615 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; gastric mucosa; ; muscle of thigh; ; left ventricle; ; gastrocnemius muscle; ; right auricle; ; skeletal muscle tissue; ; anterior pituitary; ; tibial arteries; ; right coronary artery;
	Top expressed in
	muscle of thigh; ; extensor digitorum longus muscle; ; blood; ; plantaris muscle; ; medial head of gastrocnemius muscle; ; tibialis anterior muscle; ; neural layer of retina; ; digastric muscle; ; knee joint; ; triceps brachii muscle;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein tyrosine phosphatase activity; prenylated protein tyrosine phosphatase activity; phosphatase activity; phosphoprotein phosphatase activity; hydrolase activity; protein tyrosine/serine/threonine phosphatase activity; protein binding;
Cellular component	endosome; plasma membrane; early endosome; membrane; nucleus; cytoplasm;
Biological process	Notch signaling pathway; protein dephosphorylation; positive regulation of vascular permeability; regulation of vascular endothelial growth factor signaling pathway; endothelial cell migration; dephosphorylation; peptidyl-tyrosine dephosphorylation; regulation of transcription, DNA-templated; positive regulation of NIK/NF-kappaB signaling; positive regulation of establishment of protein localization; cellular response to leukemia inhibitory factor;
	Sources:Amigo / QuickGO
Orthologs
	11156
	19245
	ENSG00000184489; ENSG00000275575
	ENSMUSG00000059895
	O75365
	Q9D658
	NM_007079; NM_032611
	NM_001166388; NM_001166389; NM_001166390; NM_008975; NM_001357591
	NP_009010; NP_116000
	NP_001159860; NP_001159861; NP_001159862; NP_033001; NP_001344520
	Wikidata
View/Edit Human	View/Edit Mouse

Protein tyrosine phosphatase type IVA 3 is an enzyme that in humans is encoded by the PTP4A3 gene.^[5]

Template:PBB Summary

References

^ ^a ^b ^c ENSG00000275575 GRCh38: Ensembl release 89: ENSG00000184489, ENSG00000275575 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000059895 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: PTP4A3 protein tyrosine phosphatase type IVA, member 3".

References

Further reading