PTPRH

PTPRH
Identifiers
Aliases	PTPRH, R-PTP-H, SAP1, protein tyrosine phosphatase, receptor type H, protein tyrosine phosphatase receptor type H
External IDs	OMIM: 602510; MGI: 3026877; HomoloGene: 37693; GeneCards: PTPRH; OMA:PTPRH - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	55,209,506 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	4,607,040 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; duodenum; ; pancreatic ductal cell; ; mucosa of transverse colon; ; gallbladder; ; mucosa of ileum; ; rectum; ; islet of Langerhans; ; oocyte; ; spleen;
	Top expressed in
	jejunum; ; ileum; ; colon; ; duodenum; ; stomach; ; striatum of neuraxis; ; superior frontal gyrus; ; cerebellar cortex; ; primary visual cortex; ; hypothalamus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein tyrosine phosphatase activity; phosphatase activity; transmembrane receptor protein tyrosine phosphatase activity; protein binding; phosphoprotein phosphatase activity; hydrolase activity;
Cellular component	cytoplasm; integral component of membrane; integral component of plasma membrane; membrane; plasma membrane; microvillus; apical plasma membrane; microvillus membrane; cell projection;
Biological process	protein dephosphorylation; dephosphorylation; apoptotic process; peptidyl-tyrosine dephosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	5794
	545902
	ENSG00000080031
	ENSMUSG00000035429
	Q9HD43
	E9Q0N2
	NM_001161440; NM_002842
	NM_207270
	NP_001154912; NP_002833
	NP_997153
	Wikidata
View/Edit Human	View/Edit Mouse

Receptor-type tyrosine-protein phosphatase H is an enzyme that in humans is encoded by the PTPRH gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000080031 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000035429 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Matozaki T, Suzuki T, Uchida T, Inazawa J, Ariyama T, Matsuda K, Horita K, Noguchi H, Mizuno H, Sakamoto C, et al. (Feb 1994). "Molecular cloning of a human transmembrane-type protein tyrosine phosphatase and its expression in gastrointestinal cancers". J Biol Chem. 269 (3): 2075–81. PMID 8294459.
^ "Entrez Gene: PTPRH protein tyrosine phosphatase, receptor type, H".

References

Further reading