Anisodine
This is an old revision of this page, as edited by Machinexa (talk | contribs) at 13:48, 21 December 2020 (https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.1986.tb10201.x It is concluded that both anisodamine and to a lesser extent anisodine possess α‐adrenoceptor blocking properties; this antagonistic activity of anisodamine may contribute to its salutary effects on the microcirculation. However, it is unlikely that anisodine produces a significant adrenoceptor blockade in the clinically used dose‐range.). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.
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Formula | C17H21NO5 |
Molar mass | 319.357 g·mol−1 |
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Anisodine, also known as daturamine and α-hydroxyscopolamine, is an antispasmodic and anticholinergic drug used in the treatment of acute circulatory shock in China.[1][2] It is a tropane alkaloid and is found naturally in plants of the family Solanaceae.[2] Anisodine acts as a muscarinic acetylcholine receptor antagonist and α1-adrenergic receptor antagonist.[1]
See also
References
- ^ a b Varma DR, Yue TL (March 1986). "Adrenoceptor blocking properties of atropine-like agents anisodamine and anisodine on brain and cardiovascular tissues of rats". British Journal of Pharmacology. 87 (3): 587–94. doi:10.1111/j.1476-5381.1986.tb10201.x. PMC 1916562. PMID 2879586.
- ^ a b Ganellin, C. R.; Triggle, David J. (21 November 1996). Dictionary of pharmacological agents - Google Books. ISBN 9780412466304.
mAChRsTooltip Muscarinic acetylcholine receptors |
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