CXCL17
| chemokine (C-X-C motif) ligand 7 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | CXCL17 | ||||||
| Alt. symbols | SCYB17, VCC-1, DMC | ||||||
| NCBI gene | 284340 | ||||||
| RefSeq | NM_198477 | ||||||
| UniProt | Q6UXB2 | ||||||
| Other data | |||||||
| Locus | Chr. 19 q13.2 | ||||||
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Chemokine (C-X-C motif) ligand 17 (CXCL17) is a small cytokine belonging to the CXC chemokine family that has been identified in humans and mice. CXCL17 attracts dendritic cells and monocytes and is regulated in tumors. It is also known as VEGF co-regulated chemokine 1 (VCC-1) and dendritic cell- and monocyte-attracting chemokine-like protein (DMC).[1][2] This chemokine is constitutively expressed in the lung.[2] The gene for human CXCL17 is located on chromosome 19.[2]
References
- ^ Weinstein E, Head R, Griggs D, Sun D, Evans R, Swearingen M, Westlin M, Mazzarella R (2006). "VCC-1, a novel chemokine, promotes tumor growth". Biochem Biophys Res Commun. 350 (1): 74–81. doi:10.1016/j.bbrc.2006.08.194. PMID 16989774.
- ^ a b c Pisabarro M, Leung B, Kwong M, Corpuz R, Frantz G, Chiang N, Vandlen R, Diehl L, Skelton N, Kim H, Eaton D, Schmidt K (2006). "Cutting edge: novel human dendritic cell- and monocyte-attracting chemokine-like protein identified by fold recognition methods". J Immunol. 176 (4): 2069–73. doi:10.4049/jimmunol.176.4.2069. PMID 16455961.
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