UBE2C

UBE2C
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1I7K, 4YII, 5A31
Identifiers
Aliases	UBE2C, UBCH10, dJ447F3.2, ubiquitin conjugating enzyme E2 C
External IDs	OMIM: 605574 MGI: 1915862 HomoloGene: 5096 GeneCards: UBE2C
EC number	2.3.2.24
Gene location (Human) Chr. Chromosome 20 (human) Band 20q13.12 Start 45,812,576 bp End 45,816,957 bp
Gene location (Mouse) Chr. Chromosome 2 (mouse) Band 2 H3|2 85.27 cM Start 164,611,818 bp End 164,620,742 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in embryo ganglionic eminence oocyte bone marrow secondary oocyte thymus trabecular bone rectum bone marrow cells stromal cell of endometrium Top expressed in medial ganglionic eminence somite otic placode abdominal wall morula blood hand endocardial cushion thymus maxillary prominence More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transferase activity nucleotide binding ubiquitin protein ligase activity ubiquitin-protein transferase activity protein binding ATP binding ubiquitin conjugating enzyme activity ubiquitin protein ligase binding ubiquitin-like protein ligase binding Cellular component cytoplasm nucleoplasm anaphase-promoting complex cytosol plasma membrane ubiquitin ligase complex nucleus Biological process free ubiquitin chain polymerization ubiquitin-dependent protein catabolic process exit from mitosis positive regulation of exit from mitosis protein K11-linked ubiquitination cell division protein K48-linked ubiquitination regulation of mitotic metaphase/anaphase transition cell cycle anaphase-promoting complex-dependent catabolic process positive regulation of ubiquitin protein ligase activity protein ubiquitination regulation of mitotic cell cycle phase transition Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 11065 68612 Ensembl ENSG00000175063 ENSMUSG00000001403 UniProt O00762 Q5TZN3 Q9D1C1 RefSeq (mRNA) NM_001281741 NM_001281742 NM_007019 NM_181799 NM_181800 NM_181801 NM_181802 NM_181803 NM_026785 RefSeq (protein) NP_001268670 NP_001268671 NP_008950 NP_861515 NP_861516 NP_861517 NP_008950.1 NP_081061 Location (UCSC) Chr 20: 45.81 – 45.82 Mb Chr 2: 164.61 – 164.62 Mb PubMed search
Wikidata
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Ubiquitin-conjugating enzyme E2 C is a protein that in humans is encoded by the UBE2C gene.