Growth factor receptor
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A growth factor receptor is a receptor which binds to growth factor.[1] Growth factor receptors are the first stop in cells where the signaling cascade for cell differentiation and proliferation begins. Growth factors, which are ligands that bind to the receptor are the initial step to activating the growth factor receptors and tells the cell to grow and/or divide.[2]
These receptors may use the JAK/STAT, MAP kinase, and PI3 kinase pathways.[3]
References
- ^ Growth+Factor+Receptors at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- ^ "Growth Factor Receptors | Tocris Bioscience". Tocris Bioscience. Retrieved 2016-03-30.
- ^ A. V. Hoffbrand; P. A. H. Moss; J. E. Pettit (2006). Essential haematology. Wiley-Blackwell. pp. 6–. ISBN 978-1-4051-3649-5. Retrieved 28 November 2010.
| Type I cytokine receptor | |||||||||||||
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| Receptor protein serine/threonine kinase | |||||||||||||
| Receptor tyrosine kinase |
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| Tumor necrosis factor receptor | |||||||||||||
| Ig superfamily | |||||||||||||
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