Epinastine

Epinastine
Systematic (IUPAC) name
	(RS)-3-amino-9,13b-dihydro-1H-dibenz(c,f)imidazo(1,5-a)azepine
Clinical data
AHFS/Drugs.com	monograph
MedlinePlus	a604011
Pregnancy cat.	C
Legal status	?
Routes	Eye drops
Pharmacokinetic data
Protein binding	64%
Half-life	12 hours
Identifiers
CAS number	80012-43-7
ATC code	R06AX24 S01GX10
PubChem	CID 3241
DrugBank	APRD00043
ChemSpider	3128
UNII	Q13WX941EF
KEGG	D07900
ChEBI	CHEBI:51032
ChEMBL	CHEMBL1106
Chemical data
Formula	C16H15N3
Mol. mass	249.311 g/mol
SMILES	eMolecules & PubChem
	InChI InChI=1S/C16H15N3/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16/h1-8,15H,9-10H2,(H2,17,18) ; Key:WHWZLSFABNNENI-UHFFFAOYSA-N ;
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Epinastine (trade names Elestat and Relestat) is an antihistamine and a mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis. It is presently produced by Allergan and marketed by Inspire in the United States.^[1] It is used as the hydrochloride salt.

[edit] References

^ Pradhan, S; Abhishek, K; Mah, F (2009). "Epinastine: topical ophthalmic second generation antihistamine without significant systemic side effects". Expert opinion on drug metabolism & toxicology 5 (9): 1135–40. doi:10.1517/17425250903117284. PMID 19630694.

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