Oxatomide

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Oxatomide
Oxatomide.png
Systematic (IUPAC) name
1-{3-[4-(diphenylmethyl)piperazin-1-yl]propyl}-1,3-dihydro-2H-benzimidazol-2-one
Clinical data
Trade names Tinset, Cedlips, Atoxan
AHFS/Drugs.com International Drug Names
  • (Prescription only)
Oral
Identifiers
60607-34-3 N
R06AE06
PubChem CID 4615
ChemSpider 4454 YesY
UNII J31IL9Z2EE YesY
KEGG D01773 YesY
ChEMBL CHEMBL13828 YesY
Chemical data
Formula C27H30N4O
426.553 g/mol
 N (what is this?)  (verify)

Oxatomide (R35443) is a first-generation antihistamine of the phenylpiperazine class.[1] It was discovered at Janssen Pharmaceutica in 1975. Oxatomide lacks any anticholinergic effects.[1] In addition to its H1 receptor antagonism, it also possesses antiserotonergic actions.[1]

See also[edit]

References[edit]

  1. ^ a b c Ohmori K, Ishii H, Nito M, Shuto K, Nakamizo N (May 1983). "[Pharmacological studies on oxatomide (KW-4354). (7) Antagonistic effects on chemical mediators]". Nippon Yakurigaku Zasshi. Folia Pharmacologica Japonica (in Japanese) 81 (5): 399–409. doi:10.1254/fpj.81.399. PMID 6138301.