JWH-116

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JWH-116
JWH-116.png
Systematic (IUPAC) name
(2-ethyl-1-pentyl-1H-indol-3-yl)-1-naphthalenylmethanone
Clinical data
Legal status Class B (UK)
Identifiers
CAS number 619294-64-3
ATC code ?
ChemSpider 29341485
Chemical data
Formula C26H27NO 
Mol. mass 369.50 g/mol

JWH-116 is a synthetic cannabinoid receptor ligand from the naphthoylindole family. It is the indole 2-ethyl derivative of related compound JWH-018. The binding affinity of JWH-116 for the CB1 receptor is reported as Ki = 52 ± 5 nM.[1]

See also[edit]

References[edit]

  1. ^ Huffman JW, Mabon R, Wu M-J, Lu J, Hart R, Hurst DP, Reggio PH, Wiley JL, Martin BR (2003). "3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor". Bioorg. Med. Chem. 11 (4): 539–549. doi:10.1016/s0968-0896(02)00451-0.