JWH-185

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JWH-185
JWH-185.png
Systematic (IUPAC) name
3-[(4-methoxy-1-naphthalenyl)methyl]-1-pentyl-1H-indole
Clinical data
Legal status Class B (UK)
Identifiers
CAS number 619294-39-2
ATC code ?
Chemical data
Formula C25H27NO 
Mol. mass 357.49 g/mol

JWH-185 is a synthetic cannabinoid receptor ligand from the naphthoylindole family. It is the carbonyl-reduced derivative of related compound JWH-081. The binding affinity of JWH-185 for the CB1 receptor is reported as Ki = 17 ± 3 nM.[1]


See also[edit]

References[edit]

  1. ^ Huffman JW, Mabon R, Wu M-J, Lu J, Hart R, Hurst DP, Reggio PH, Wiley JL, Martin BR (2003). "3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor". Bioorg. Med. Chem. 11 (4): 539–549. doi:10.1016/s0968-0896(02)00451-0.