MK-9470

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MK-9470
MK-9470.png
Names
IUPAC name
N-((2S,3S)-3-(3-cyanophenyl)-4-(4-ethoxyphenyl)butan-2-yl)-2-methyl-2-(5-methylpyridin-2-yloxy)propanamide
Identifiers
945850-36-2
ChemSpider 9342440
Jmol-3D images Image
PubChem 11167344
Properties
C29H33N3O3
Molar mass 471.59 g/mol
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

MK-9470 is a synthetic compound, which binds to the CB1 cannabinoid receptor and functions as an inverse agonist.[1]

References[edit]

  1. ^ Burns HD, Van Laere K, Sanabria-Bohórquez S, Hamill TG, Bormans G, Eng WS, Gibson R, Ryan C, Connolly B, Patel S, Krause S, Vanko A, Van Hecken A, Dupont P, De Lepeleire I, Rothenberg P, Stoch SA, Cote J, Hagmann WK, Jewell JP, Lin LS, Liu P, Goulet MT, Gottesdiener K, Wagner JA, de Hoon J, Mortelmans L, Fong TM, Hargreaves RJ (2007). "[18F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor". Proc. Natl. Acad. Sci. U.S.A. 104 (23): 9800–5. Bibcode:2007PNAS..104.9800B. doi:10.1073/pnas.0703472104. PMC 1877985. PMID 17535893.