Alpha-D2PV

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by Meodipt (talk | contribs) at 20:32, 30 March 2024 (Created page with '{{Drugbox | drug_name = Alpha-D2PV | IUPAC_name = | image = diphenylpyrrolidinylethanone_structure.png | width = 200px <!--Clinical data--> | tradename = | routes_of_administration = | legal_UK = Class B | legal_DE = Anlage II | legal_US = <!--Identifiers--> | CAS_number = 27590-61-0 | UNII = | PubChem = 33957 | ChemSpiderID = | synonyms = <!--Chemical data--> | C=18 | H=19 | N=1 | StdInChI= 1S/C18H19NO/c20-18(16-11-5-2-6-12-16)17(19-13-7-8-14-19...'). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff)
Alpha-D2PV
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
Chemical and physical data
FormulaC18H19N
Molar mass249.357 g·mol−1
3D model (JSmol)
  • C1CCN(C1)C(C2=CC=CC=C2)C(=O)C3=CC=CC=C3
  • InChI=1S/C18H19NO/c20-18(16-11-5-2-6-12-16)17(19-13-7-8-14-19)15-9-3-1-4-10-15/h1-6,9-12,17H,7-8,13-14H2
  • Key:GQCCTZGWWWUYLS-UHFFFAOYSA-N

Alpha-D2PV (DPPE) is a substituted cathinone derivative which has been sold as a designer drug. It was invented in the 1950s,[1] and first identified by forensic laboratories as a designer drug in 2020, though anecdotal reports suggest it may have emerged earlier than this. It is similar in structure to the potent designer stimulant drug alpha-PVP but with the propyl side chain replaced by a phenyl ring, and while it is a less potent stimulant than alpha-PVP itself, Alpha-D2PV has been known to cause poisoning when misrepresented as less potent drugs such as MDMA. While it is also similar in structure to the dissociative drug diphenidine, Alpha-D2PV appears to produce only stimulant effects.[2][3][4]

See also

References

  1. ^ US 2773069
  2. ^ Kuropka P, Zawadzki M, Szpot P (2023). "A review of synthetic cathinones emerging in recent years (2019-2022)". Forensic Toxicology. 41 (1): 25–46. doi:10.1007/s11419-022-00639-5. PMC 9476408. PMID 36124107.
  3. ^ Puljević C, Tscharke B, Wessel EL, Francis C, Verhagen R, O'Brien JW, Bade R, Nadarajan D, Measham F, Stowe MJ, Piatkowski T, Ferris J, Page R, Hiley S, Eassey C, McKinnon G, Sinclair G, Blatchford E, Engel L, Norvill A, Barratt MJ. Characterising differences between self-reported and wastewater-identified drug use at two consecutive years of an Australian music festival. Sci Total Environ. 2024 Apr 15;921:170934. doi:10.1016/j.scitotenv.2024.170934 PMID 38360330
  4. ^ Wood MR, Bernal I, Lalancette RA. Crystal structure and analytical profile of 1,2-diphenyl-2-pyrrolidin-1-ylethanone hydrochloride or `α-D2PV': a synthetic cathinone seized by law enforcement, along with its diluent sugar, myo-inositol. Acta Crystallogr C Struct Chem. 2024 Apr 1. doi:10.1107/S2053229624000561 PMID 38441142