Pentylone

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Pentylone
Pentylone.svg
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC13H17NO3
Molar mass235.278 g/mol
3D model (JSmol)
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Pentylone (β-Keto-Methyl​benzo​dioxolyl​pentanamine, βk-Methyl-K, βk-MBDP, methyl​enedioxy​pentedrone, or 1‐(3,4‐methylenedioxyphenyl)‐2‐(methylamino)pentan‐1‐one[1]) is a stimulant developed in the 1960s.[2] It is a substituted cathinone (a type of substituted phenethylamine). It has been identified in some samples of powders sold as "NRG-1", along with varying blends of other cathinone derivatives including flephedrone, MDPBP, MDPV and 4-MePPP. It was also found in combination with 4-MePPP being sold as "NRG-3".[1] Reports indicate side effects include feelings of paranoia, agitation and inability to sleep, with effects lasting for several days at high doses.[3]

Pharmacology[edit]

Pentylone acts as a serotonin-norepinephrine-dopamine reuptake inhibitor and a serotonin releasing agent.[4]

Legality[edit]

Pentylone is banned in Canada, Germany, Sweden and also in the United States and in the UK.[5][6]

See also[edit]

References[edit]

  1. ^ a b Brandt SD, Freeman S, Sumnall HR, Measham F, Cole J (December 2010). "Analysis of NRG 'legal highs' in the UK: identification and formation of novel cathinones". Drug Testing and Analysis. 3 (9): 569–75. doi:10.1002/dta.204. PMID 21960541.
  2. ^ Substituted phenyl-α-amino ketones. British Patent GB 1085135 (1969).
  3. ^ Joe Bish (Aug 4, 2017). "Watch Out for Pentylone, the Horrible New MDMA Additive". Vice.
  4. ^ Simmler, L. D.; Rickli, A.; Hoener, M. C.; Liechti, M. E. (2014). "Monoamine transporter and receptor interaction profiles of a new series of designer cathinones". Neuropharmacology. 79: 152–60. doi:10.1016/j.neuropharm.2013.11.008. PMID 24275046.
  5. ^ "Cannabinoider föreslås bli klassade som hälsofarlig vara" (in Swedish). Retrieved 29 June 2015.
  6. ^ Schedules of Controlled Substances: Temporary Placement of 10 Synthetic Cathinones Into Schedule I