| {{2021 AFC East standings}} {{2021 AFC North standings}} {{2021 AFC South standings}} {{2021 AFC West standings}} {{colorbox|#cfc|x}} Clinched playoff berth.<br/>{{colorbox|#cfc|y}} Clinched division title.<br/>{{colorbox|#cfc|z}} Clinched first-round bye.<br/>{{colorbox|#cfc|*}} Clinched home-field advantage bye.
| {{2021 AFC East standings}} {{2021 AFC North standings}} {{2021 AFC South standings}} {{2021 AFC West standings}} {{colorbox|#cfc|x}} Clinched playoff berth.<br/>{{colorbox|#ccc|†}} Eliminated from playoff contention.<br/>
| {{2021 NFC East standings}} {{2021 NFC North standings}} {{2021 NFC South standings}} {{2021 NFC West standings}} {{colorbox|#cfc|y}} Clinched division title.<br/>{{colorbox|#cfc|z}} Clinched first-round bye.<br/>{{colorbox|#cfc|*}} Clinched home-field advantage.
| {{2021 NFC East standings}} {{2021 NFC North standings}} {{2021 NFC South standings}} {{2021 NFC West standings}} {{colorbox|#ccc|†}} Eliminated from playoff contention.<br/><br/><br/>
^ abTennessee finished ahead of Kansas City based on head-to-head victory.
^ abLas Vegas finished ahead of New England based on win percentage in common games (5–1 vs. 2–4 against: Miami, Dallas, LA Chargers, Cleveland, and Indianapolis).
^ abcIndianapolis finished ahead of Miami and Los Angeles based on conference record (7–5 vs. 6–6).
^ abMiami finished ahead of LA Chargers based on win percentage in common games (5–1 vs. 2–4 against: New England, Las Vegas, Houston, Baltimore, and NY Giants).
^ abCleveland finished ahead of Baltimore based on division record (3–3 vs. 1–5).
^ abNY Jets finished ahead of Houston based on head-to-head victory.
^When breaking ties for three or more teams under the NFL's rules, they are first broken within divisions, then comparing only the highest-ranked remaining team from each division.
^ abGreen Bay finished ahead of Tampa Bay based on conference record (9–3 vs. 8–4).
^ abDallas finished ahead of LA Rams based on conference record (10–2 vs. 8–4).
^ abPhiladelphia finished ahead of New Orleans based on head-to-head victory.
^ abcWashington finished ahead of Atlanta and Seattle based on head-to-head victories.
^ abSeattle finished ahead of Atlanta based on win percentage in common games (4–2 vs. 3–3 against: San Francisco, New Orleans, Jacksonville, Washington, and Detroit).
^When breaking ties for three or more teams under the NFL's rules, they are first broken within divisions, then comparing only the highest-ranked remaining team from each division.